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RU58841 Guide

November 28, 2016 By Hairguru Leave a Comment

Ru58841 Video Guide tutorialThis guide will give you a clear overview of how RU-58841 solution is constituted for your research purpose.

Indonesia is currently the only country in the world where RU58841 is available at the pharmacies as an “FDA approved” anti hair loss topical without a prescription.

If you don’t live in Indonesia and still want to conduct your research, then there is still hope. There is still a way to get your hands on pure RU58841. Just make sure that the purity of RU58841 meets the golden standard of 99% purity minimum!

RU58841 Topical premixed solutions

Some companies sell Ru58841 in a topical pre-mixed solution which is stable for 6-12 months depending on how the solution is stored. Most users are using the pre-mixed topical solutions, however topical RU solutions are more expensive than when you mix your own RU58841 solution. The mixing process is very easy and it literally comes down to dissolving the pure RU58841 powder into an ethanol containing solution. Almost all hair loss topicals contain a high amount of ethanol. These are topicals such as Minoxidil  or Neogenic. Knowing this fact, makes it easy to pick a topical that you already use, and treat this topical as a “vehicle/ carrier” to dissolve the raw RU55841 powder.

 

Mixing RU58841 into 60 ML Minoxidil

If you are a Minoxidil user then you might just want to create your own 60 ML (2oz) all in one solution.  The steps are very simple and straightforward, even if you are just starting out with your research or bio/chemist class.

Easy steps to mix your own RU58841 minoxidil solution:

Step 1: Get pure 99%+ RU58841
Step 2: Measure exactly 3 gram RU58841 and pour it into your 5% minoxidil solution
Step 3: It is now time to shake the solution so that all RU58841 powder dissolves well. This process can take up to 5 minutes or sometimes even longer.

The result is: 5% minixidil solution with 5% Ru58841 inside.

Some issues might arise during this last step. Posible solutions are given in the FAQ at the bottom of this page.

Some nice video tutorials on youtube:

This YouTuber shows how to mix 3 grams RU58841 into a Minoxidil solution to obtain a 5% solution:

Mixing RU58841 into 50ML 5% PG/Ethanol solution

Easy steps by step guide to mix your own 5% RU solution

Step 1: Get ultra pure 99%+ RU58841
Step 2: Measure 2.5 Gram RU58841 and pour it into the plastic/pet bottle.  You can use aluminum foil if you don’t have a funnel.
Step 3: Measure exactly 35 ML ethanol and pour it into the bottle. (you can use a syringe, pipette or measuring cup)
Step 4: Measure exactly  15 ML Propylene Glycol (pg) and pour it into the bottle.
Step 5: It is now time to shake the solution so that all RU58841 powder dissolves well. This process can take up to 5 minutes or sometimes even longer.

Another nice video tutorial  about mixing ru58841 into pg + ethanol:

 

Sources and equipment:

everclear 95% pureEthanol

If you live in the United States then just grab a bottle of “EVERCLEAR GRAIN ALCOHOL 190 PROOF 750ML” which can be purchased in most liquor stores.

If you live in Europe then you have to look for the brand “brennerei–kessler“. They also sell ultra pure 96% ethanol via Ebay and Amazon .

Ethanol is used to dissolve the RU58841 so that the RU powder/particles transforms from powder into a solution.

 

PG

Propylene glycol (PG)

PG can be purchased anywhere and is also a compound that is commonly used in cosmetics.
PG is added to the ethanol solution so that the ethanol doesn’t dry out too easily and remains for a while on the research subject.

 

 

0.01 scale
0.01 scale

0.01 Scale

Get yourself a “0.01 scale”. Easy to find via Amazon and Ebay. Most 0.01 scales are cheap, very easy to use and don’t need much of a calibration.

 

 

FAQ About Mixing RU58841 Solutions and answers for common mistakes

Solubility at Room temperature

If the temperature is low (cold solution), then the RU58841 particles will probably have a hard time to fully dissolve into the solution (minox solution or pg/ethanol solution). Make sure the temperature of the solution is at least 20-25 C + before you mix the powder.

Grain/particle/ mesh size of RU58841 (different visual appearance of the powder)

The grain/mesh size of the RU58841 might be different per batch. Some batches have bigger crystals than other. This is just the appearance of the powder. The grain/mesh size has fortunately nothing to do with the purity or quality of any chemical powder. You can have very big grains that dissolve slightly harder and you can have ultra fine powder. As long the powder is tested by a lab and is 99% pure, you are good to go.

Why is there difference in the size (mesh) of the RU58841 crystals?
  1. RU58841 is a molecule, very small with a molar mass 369.3 g/mol, not viable with the human eye.
  2. At the end of the production process, once the Ru58841 is purified and 99% pure, it is converted to Crystals. This is the so called crystallization process.
  3. What happens in the crystallization process is the following:
    1. The RU58841 (small molecules) are stacked together and the result is that it looks like crystals or crystal powder.
    2. These crystals differ from size  in each crystalization cycle. Sometimes they are bigger, sometimes they are smaller. This is just the appearance (how-many molecules are stacked together in 1 crystal)
So do not be mislead by the appearance of any chemical. Once a research product such as RU58841 is dissolved into a solution, it loses its grain/powder/ crystal "form" and the crystals get converted into soluble RU58841 molecules floating around in your ethanol vehicle. The only correct method to measure the purity of the RU powder is in a laboratory by HPLC/NMR/IR/LCMS test methods. The powder can not be judged by its visual Appearance.

RU solubility in different minoxidil brands

Some minoxidil brands have a very low ethanol content which makes it very hard for RU58841 to fully dissolve into the solution. RU58841 is very soluble in pure (95-96%) ethanol.

Kirkland is one of the brands that contain low amount of ethanol (Just 30%). This makes it hard to dissolve RU58841. In practice this just means that you need to shake the solution a littler longer. Just put some effort here, researcher!

How Do I mix a different RU Strentgh (1% - 3%- 8%)

Good question!

The answer is straightforward and simple! For each percent strength, you need to dissolve 10mg RU powder per milliliter vehicle. (this can be Kirkland or pg/ethanol or another vehicle).

Example 1:

For a 1% solution; You need to dissolve 10MG per milliliter vehicle. In a 50 ML vehicle that would be 10mg*50 Ml = 500 MG total powder. In a 60 ML minox vehicle it would be 10 MG *60 ML = 600 MG total powder.

Example 2:

For a 3% solution; You need to dissolve 30MG per milliliter vehicle. In a 50 ML vehicle that would be 30mg*50 Ml = 1500MG (1.5 gram) total powder. In a 60 ML minox vehicle it would be 30 MG *60 ML = 1800 MG (1.8 gram) total powder.

Example 3:

For a 8% solution; You need to dissolve 80MG per milliliter vehicle. In a 50 ML vehicle that would be 80mg*50 Ml = 4000MG (4 gram) total powder. In a 60 ML minox vehicle it would be 80 MG *60 ML = 4800MG (4.8 gram) total powder.

It is pretty simple right?

 

Check this page out for Most asked questions regarding RU.

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